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ANTIMICROBIAL RESISTANCE AND EXTENDED SPECTRUM BETA-LACTAMASE: TYPE, EPIDEMIOLOGY AND TREATMENT
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Table of contents
CHAPTER ONE 1
1.1 Introduction 1
CHAPTER TWO 5
2.1 Antibiotic Resistance 5
2.2 Genetic Of Antibiotic Resistance 6
2.3 Mechanisms of Antibiotic Resistance 9
2.4 Causes of Antibiotic Resistance 14
CHAPTER THREE 21
3.1 Antibiotic Resistance of Esbl Producing Enterobacteriaceae 21
3.2 ESBL Classification 27
3.2.1. Functional Classification 28
3.2.2 Molecular Classification 30
3.3 Types of ESBL 31
3.4 Epidemiology of ESBLS 33
3.4.1 Epidemiology of Extended Spectrum Lactamase in South and Central America 33
3.4.2 Epidemiology of Extended Spectrum Lactamase in North America 33
3.4.3 Epidemiology of Extended Spectrum Lactamase in Europe 34
3.4.4 Epidemiology of Extended Spectrum Lactamase in Africa 36
3.4.5 Epidemiology of Extended Spectrum Lactamase in Middle East 37
3.4.6 Epidemiology of Extended Spectrum Lactamase in Australia 38
3.4.7 Epidemiology of Extended Spectrum Lactamase in Asia 39
3.4.8 Epidemiology of Extended Spectrum Lactamase in Nigeria 41
CHAPTER FOUR 42
4.1 Transmission of ESBLS 42
4.1.1 Clonal expansion 42
4.1.2 Horizontal dissemination 43
4.2 Techniques for Combating Antibiotic Resistance 45
4.3 Prevention and Control Management of ESBL 46
4.4 Treatment and Management of Esbl Infection 47
CHAPTER FIVE: Conclusion 49
References 53
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