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ISOLATION AND CHARACTERISATION OF MALASSEZIA SPECIE FROM STUDENTS OF OLABISI ONABANJO UNIVERSITY
Categories
Table of contents
CHAPTER ONE 1
1.1 Introduction 1
1.2 General Objective 3
1.3 Specific Objectives 3
1.4 Significance of the Study 3
CHAPTER TWO: Literature Review 4
2.1 Malassezia 4
2.2 Pathophysiology on Human Skin 7
2.3 Risk Factors for Malassezia Fungemia and Disseminated Disease 9
2.4 Malassezia-Associated Skin Diseases 10
2.4.1 Pityriasis versicolor 10
2.4.2 Seborrheic dermatitis and dandruff 10
2.4.3 Atopic dermatitis 11
2.4.4 Malassezia folliculitis 11
2.4.5 Psoriasis 12
2.5 Detection of Malassezia Infections in Humans and Animals 13
2.6 Susceptibility Testing and Treatment 15
CHAPTER THREE: Materials and Methods 18
3.1 Collection of Samples 18
3.2 Sterilization of Glassware 18
3.3 Microbiological Evaluation 18
3.4 Malassezia Species Identification 19
3.4.2 Catalase Test 19
CHAPTER FOUR: Results 20
CHAPTER FIVE 25
5.1 Discussion 25
5.2 Conclusion and Recommendations 27
References 28
LIST OF TABLES
Table Title Pages
4.1 Frequency and Percentage of Malassezia Species Isolated from Eczema
and Dandruff 24
Abstract
Malassezia species are known as the microflora of human skin that can induce superficial skin infections. The present study was carried out to determine the prevalence rate of Malassezia spp. among the students of the Olabisi Onabanjo University, Ago-Iwoye. Twenty (20) samples comprising of 10 samples of dandruff and 10 samples of eczema were collected randomly from twenty (20) students. A total twenty Malassezia spp. were identified based on their macroscopic, microscopic and physiological properties. The identified Malassezia spp. were Malassezia furfur, Malassezia restricta and Malassezia glubosa. The percentage occurrence of the isolated organisms showed 7 (35%) for Malassezia furfur, 7 (35%) for Malassezia glubosa and 6(30%) for Malassezia restricta. The presence of Malassezia spp. can cause severe disease, hence, the treatment of these infections should not be taken with levity. Medical practitioners should be consulted in cases associated with eczema and dandruff instead of self-medications.
Keyword: Malassezia species, Microflora, Skin infection, Dandruff, Eczema.
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